Functional Elements within the Dynein Microtubule-binding Domain
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چکیده
منابع مشابه
Functional elements within the dynein microtubule-binding domain.
Dynein interacts with microtubules through an ATP-sensitive linkage mapped to a structurally complex region of the heavy chain following the fourth P-loop motif. Virtually nothing is known regarding how binding affinity is achieved and modulated during ATP hydrolysis. We have performed a detailed dissection of the microtubule contact site, using fragment expression, alanine substitution, and pe...
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www.sciencemag.org (this information is current as of December 18, 2008 ): The following resources related to this article are available online at http://www.sciencemag.org/cgi/content/full/322/5908/1691 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/322/5908/1691/DC1 can be f...
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ژورنال
عنوان ژورنال: Molecular Biology of the Cell
سال: 2000
ISSN: 1059-1524,1939-4586
DOI: 10.1091/mbc.11.2.523